Use of D,L-alpha-lipoic acid, its enantiomers and/or its derivatives as additive for erythrocyte liquid preserves and cryopreserves for homologous and autologous erythrocyte concentrates

摘要

The use of cpds. (A) is claimed as an additive for cryo-preserved erythrocytes (I) or for erythrocyte preservation liq. (II) for homologous and autologous erythrocyte concentrates. (A) is D,L- alpha -lipo acid and/or its enantiomers and/or derivs. Also claimed are: (1) the prodn. of an erythrocyte concentrate using CPDA-1 (undefined) and SAG-M (undefined) and other stabilisers, where (A) is added into the tubing system or directly into the bottle, and (2) prodn. of erythrocyte cryo-preservative contg. (A) by treating with hydroxyethyl starch, and thawing then processing further with a cell (blood) saver.