Peritoneal dialysis solutions and their use to minimize injury to mesothelial cells

摘要

A peritoneal dialysis solution comprises physiological salts in concentrations sufficient to affect the removal of solutes by diffusion from the patient's blood across the peritoneal membrane into the solution. The solution includes at least one compound selected from vitamin E, procysteine, and superoxide dismutase to scavenge free radicals generated by activated peritoneal macrophages during peritonitis. The invention also uses these compounds, or chondroitin sulphate in the manufacture of a dialysis solution, for preventing injury to mesothelial cells.