Selective Deprotection Method of Cefme Derivatives Having Diphenylmethyl Protection Group

摘要

The present invention relates to an economical method for selectively deprotecting and reacting only diphenylmethyl protecting groups by reacting a cefe derivative of the following general formula (I) with an alkali metal iodide salt in a water-soluble organic solvent or a mixed solvent of water and a water-soluble organic solvent. will be.;[Wherein, R ₁ is or And R ₂ is —OH, —Cl or —CH ₂⁺ N≡R ₃ (R ₃ is an alkyl group, a cycloalkyl group, an aromatic ring or a derivative thereof)]