A highly sensitive and accurate automated method for identifying and quantifying platelets and determining platelet activation status using whole blood samples

摘要

The present invention is to provide an accurate method and system that is highly sensitive and capable of quantifying and quantifying platelets in whole blood samples using automated blood devices. The method and system of the present invention provides an accurate measurement of platelet dry mass and platelet component concentration in abnormal blood samples of patients with thrombocytopenic purpura. Platelet dry mass and platelet count The determination of platelet activation is more effective than activated platelets because activated platelets exhibit lower concentrations and refractive indices than activated platelets. The methods and systems of the present invention also allow a clinician or practitioner with skill to determine the aging of a blood sample based on measured parameters of platelet component concentration.