Process for improving enantiomeric purity of aldehydes (Process for improving enantiomeric purity of aldehydes)

摘要

(1) an initial solution containing a non-eutectic mixture of a first aldehyde and a second aldehyde, wherein the non-eutectic mixture only crystallizes when the solubility limit of the first aldehyde in the initial solution exceeds the second aldehyde (2) maintaining the initial solution at a temperature above the eutectic temperature of the non-eutectic mixture and above the solubility limit of the first aldehyde so that the second aldehyde is relatively less than the amount present in the initial solution (Primary aldehyde) containing a reduced amount of a corresponding enantiomer, isomeric aldehyde (secondary aldehyde), including the step of forming a crystalline aldehyde containing a small amount will be.