4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENE CARBOXYLIC ACID ARYLALKYLESTERS SHOWING ANTIINFLAMMATORY ACTIVITY, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION SHOWING ANTIINFLAMMATORY ACTIVITY

摘要

FIELD: organic chemistry. SUBSTANCE: product: 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracene carboxylic acid arylalkyl esters that were synthesized from 4,5-diacetooxy-9,10-dihydro-9,10-dioxo-2-anthracene carboxylic acid chloroanhydride by treatment with alcohol of the formula RCH₂OH where: R - CH₂O - alcohol residue RCH₂OH, followed by treatment with weak alkali solution. Pharmcomposition contains this agent at amount 5-500 mg per a single dose. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 6 cl