wherein R1 is hydrogen; R2 is pyrine or pyrimidine base, analogue or derivative thereof; Z is S, S is 0 or SO2, and pharmaceutically acceptable derivatives thereof. Present invention also describes use of said compounds as antiviral agents, pharmaceutical compositions and methods of preparing said compounds. EFFECT: improved properties. 26 cl, 3 tbl"/> 1,3-OXATHIOLANE, GEOMETRICAL AND OPTICAL ISOMERS THEREOF, MIXTURES OF SAID ISOMERS, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY
首页> 外国专利> 1,3-OXATHIOLANE, GEOMETRICAL AND OPTICAL ISOMERS THEREOF, MIXTURES OF SAID ISOMERS, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY

1,3-OXATHIOLANE, GEOMETRICAL AND OPTICAL ISOMERS THEREOF, MIXTURES OF SAID ISOMERS, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY

机译:1,3-氧杂环丁烷,其几何和光学异构体,所述异构体的混合物,其制备方法,以及具有抗病毒活性的药物组合物

摘要

FIELD: pharmaceutical industry. SUBSTANCE: present invention describes compounds of formula: wherein R1 is hydrogen; R2 is pyrine or pyrimidine base, analogue or derivative thereof; Z is S, S is 0 or SO2, and pharmaceutically acceptable derivatives thereof. Present invention also describes use of said compounds as antiviral agents, pharmaceutical compositions and methods of preparing said compounds. EFFECT: improved properties. 26 cl, 3 tbl
机译:领域:制药业。物质:本发明描述了下式的化合物:其中R 1 是氢; R 2 是吡啶或嘧啶碱基,其类似物或衍生物; Z为S,S为0或SO 2 ,及其药学上可接受的衍生物。本发明还描述了所述化合物作为抗病毒剂的用途,药物组合物和制备所述化合物的方法。效果:改善了性能。 26厘升,3汤匙

著录项

  • 公开/公告号RU2092485C1

    专利类型

  • 公开/公告日1997-10-10

    原文格式PDF

  • 申请/专利权人 BIOKEM FARMA INK. (CA);

    申请/专利号SU19904743202

  • 申请日1990-02-07

  • 分类号C07D411/04;C07D327/04;A61K31/35;

  • 国家 RU

  • 入库时间 2022-08-22 03:15:43

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