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as a means of combating the multiple resistant tumorenverwendbare diarylalkylpiperidine
as a means of combating the multiple resistant tumorenverwendbare diarylalkylpiperidine
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机译:作为对抗多重耐药性肿瘤的一种方法
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PCT No. PCT/US93/12300 Sec. 371 Date Mar. 11, 1996 Sec. 102(e) Date Mar. 11, 1996 PCT Filed Dec. 17, 1993 PCT Pub. No. WO94/17040 PCT Pub. Date Aug. 4, 1994Diarylalkyl piperidines of formula (1) IMAGE (1) reverse drug resistance in multi-drug resistant tumors. These compounds apparently function by inhibiting a p-glycoprotein pump which becomes activated in late stage tumor development and which is inherently present in tumors from certain origins.
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