首页> 外国专利> Method for predicting the evolution of an infection with hepatitis c, and it is necessary for implementing it.

Method for predicting the evolution of an infection with hepatitis c, and it is necessary for implementing it.

机译:预测丙型肝炎感染演变的方法,并且有必要实施。

摘要

A method for the prognosis of the evolution of a hepatitis C viral infection towards an aggressive chronic condition in an already infected subject with a normal transaminase rate includes searching for antibodies against the hepatitis C virus, wherein the search is conducted only for antibodies against the protein NS5 and not for antibodies against other proteins of the virus. If anti-NS5 antibodies are present, a risk of evolution towards an aggressive chronic condition is determined, and an early antiviral and/or immunopotentiating treatment can be prescribed. A kit for implementing said prognosis method is also described, which contains, as the only reagent capable of being recognised by the antibodies against a hepatitis C virus protein, a reagent specifically recognised by anti-NS5 antibodies and not by antibodies against other proteins of the hepatitis C virus.
机译:在转氨酶水平正常的情况下,在已经感染的受试者中预后丙型肝炎病毒感染向侵略性慢性病发展的方法包括寻找针对丙型肝炎病毒的抗体,其中仅进行针对该蛋白质的抗体的搜索NS5,而不是针对病毒其他蛋白的抗体。如果存在抗NS5抗体,则可以确定其发展为侵略性慢性病的风险,并可以开具早期抗病毒和/或免疫增强治疗的处方。还描述了用于实施所述预后方法的试剂盒,其包含能够被抗丙型肝炎病毒蛋白的抗体识别的唯一试剂,被抗NS5抗体特异性识别的试剂而不是被抗NS5蛋白的抗体特异性识别的试剂。丙型肝炎病毒。

著录项

  • 公开/公告号FR2734639B1

    专利类型

  • 公开/公告日1997-10-03

    原文格式PDF

  • 申请/专利权人 PARTEUROP;

    申请/专利号FR19950006248

  • 发明设计人 TARDY JEAN CLAUDE;NEGRIER CLAUDE;

    申请日1995-05-26

  • 分类号G01N33/569;

  • 国家 FR

  • 入库时间 2022-08-22 03:12:17

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