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DRESSING FOR CHRONIC WOUNDS, ESPECIALLY pressure sores, IN CHINESE GEL

机译:中国胶对慢性伤口特别是压疮的治疗

摘要

A dressing for protecting and healing lesions such as chronic wounds and particularly sloughs. The dressing consists of an acetylated chitosan or chitin gel with a degree of acetylation of at least 60 %. Advantageously, the amount of chitin or chitosan is preferably of 0.5-3.5 % based on the weight of the gel and its thickness is of 3-4 mm. The method for preparing said dressing comprises forming a hydroalcoholic chitosan solution containing approximately 10 g of chitosan per litre of an alcoholic medium containing 10-65 % alcohol, stirring into said chitosan solution a reacetylation solution of acetic anhydride in the same alcohol as that contained in the hydroalcoholic solution, pouring the resulting solution into a mould having the shape of the desired dressing, allowing the gel to set, removing excess solvent, and washing the gel thoroughly.
机译:一种用于保护和治愈伤口(例如慢性伤口,特别是腐烂病)的敷料。敷料由乙酰化壳聚糖或几丁质凝胶组成,乙酰化度至少为60%。有利地,基于凝胶的重量,几丁质或壳聚糖的量优选为0.5-3.5%,并且其厚度为3-4mm。制备所述敷料的方法包括形成每升含有10-65%醇的醇介质中含有约10 g壳聚糖的水醇壳聚糖溶液,在与所述壳聚糖溶液中相同的醇中搅拌乙酸酐的重乙酰化溶液。将水醇溶液倒入具有所需敷料形状的模具中,使凝胶凝固,除去过量的溶剂,并彻底洗涤凝胶。

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