NEW GALENIC FORMULATIONS OF FENOFIBRATE AND THEIR APPLICATIONS

摘要

A galenic fenofibrate (I) formulation comprises a soln. of (I) in a solubiliser consisting of the nonionic surfactant diethylene glycol monoethyl ether (II). Also claimed are (i) a pharmaceutical compsn. for oral admin. comprising the (I) formulation in a soft capsule, pref. of gelatine, (ii) a method for solubilising (I) by incorporating (I) particles of size below 10 mu m in (II), (iii) the use of (II) as solubiliser for (I) and (iv) a method for improving the bioavailability of (I) by dissolution in (II).