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Method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins
Method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins
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机译:双-四氢呋喃基壬基产乙酸素的合成方法
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摘要
A method for the synthesis of bis-tetrahydrofuranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis- tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)- hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.
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