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Assay for N-terminal type I collagen telopeptide that survives bone resorption in vivo
Assay for N-terminal type I collagen telopeptide that survives bone resorption in vivo
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机译:在体内骨骼吸收中存活的N端I型胶原端肽的测定
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摘要
A method for assaying bone resorption rates which consists of quantitating the concentration of peptide fragments derived from bone collagen, found in a body fluid is disclosed. The method includes immunometric assay, fluorometric assay and electrochemical titration. The structure of specific peptide fragments having 3-hydroxypyridinium cross- links found in urine of Paget's disease patients and procedures for making monoclonal antibodies is described.
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