Its gene sequence and protein suppression of neuronal apoptosis, and mutation of the gene that causes spinal muscular atrophy

摘要

(57) gene of spinal muscular atrophy is a [summary] autosomal recessive neurodegenerative anomaly has been mapped to a region of chromosome 5. From that it codes for a protein having homology with apoptosis inhibitor protein of the virus, the protein encoded, this gene was designated neuronal apoptosis inhibitor protein and (NAIP). There is a deletion in (NAIP) area, patient type I, II, III spinal muscular atrophy (SMA) was observed Shitsuwa missing such a normal, non-SMA population.