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Methods and compositions for the screening of the calcium channel blocker presynaptic

机译:筛选突触前钙通道阻滞剂的方法和组合物

摘要

(57) The methods and compositions for the identification of compounds that block the release of the [summary] neurotransmitter is disclosed. Using the methods of the present invention, candidate compounds may be screened for ability to bind to the presynaptic calcium channels docking of presynaptic vesicles to calcium channels such as presynaptic inhibition. The present invention also, I disclose peptides useful in the screening methods.
机译:(57)公开了用于鉴定阻断[摘要]神经递质释放的化合物的方法和组合物。使用本发明的方法,可以筛选候选化合物结合到突触前钙通道对接的能力,例如,突触前抑制。本发明还公开了可用于筛选方法的肽。

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