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PROPHYLACTIC AND/OR TREATING AGENT FOR HYPERPHOSPHATEMIA

机译:高磷血症的预防性和/或治疗剂

摘要

PROBLEM TO BE SOLVED: To obtain a prophylactic and/or treating agent for a hyperphosphatemia, containing a pharmaceutically acceptable anion exchange resin as an active ingredient and useful for a prophylaxis and/or a treatment for a hyperphosphatemia caused by a disease of a functional disturbance of kidney. ;SOLUTION: This prophylactic and/or treating agent for a hyperphosphotemia comprises a pharmaceutically acceptable anion exchange resin (preferably the one selected from a 2-methylimidazole-epichlorohydrin copolymer, a cholestyramine resin and a colestipol, especially the 2-methylimidazole- epichlorohydrin copolymer). The effect of the treating agent is based on actions reducing both a phosphorous content in blood and a phosphorous discharge in urine. The treating agent can be orally administered. The treating agent for the oral dosing contains generally 5-95wt.%, preferably 25-90wt.% active ingredient.;COPYRIGHT: (C)1997,JPO
机译:解决的问题:获得高磷血症的预防和/或治疗剂,其包含药学上可接受的阴离子交换树脂作为活性成分,并且用于预防和/或治疗由功能障碍疾病引起的高磷血症肾脏;解决方案:这种高磷血症的预防和/或治疗剂包括药学上可接受的阴离子交换树脂(最好是选自2-甲基咪唑-表氯醇共聚物,消胆胺树脂和初苯乙二酚,尤其是2-甲基咪唑-表氯醇共聚物) 。处理剂的作用是基于减少血液中磷含量和尿液中磷排放量的作用。可以口服施用治疗剂。用于口服给药的处理剂通常包含5-95wt。%,优选25-90wt。%的活性成分。;版权所有:(C)1997,JPO

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