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Reagent to prepare a radiopharmaceutical scintigraphic imaging agent and complex radiotherapeutic composition kit to prepare a radiopharmaceutical preparation process to label a reagent to form an image of a site and to make a reagent composition of matter and use of the reagent
Reagent to prepare a radiopharmaceutical scintigraphic imaging agent and complex radiotherapeutic composition kit to prepare a radiopharmaceutical preparation process to label a reagent to form an image of a site and to make a reagent composition of matter and use of the reagent
This invention relates to radiotherapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic and radiotherapeutic agents. Specifically, the invention relates to VIP receptor binding peptides, derivatives and analogues of VIP, and embodiments of such peptides radiolabeled with a radioisotope, as well as methods and kits for making, radiolabeling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to VIP receptor binding peptide derivatives and analogues of VIP radiolabeled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention also specifically relates to VIP receptor binding peptide derivatives and analogues of VIP radiolabeled with cytotoxic radioisotopes such as rhenium-186 (186Re) and rhenium-188 (188Re) for use as radiotherapeutic agents. Methods and kits for making, radiolabeling and using such peptides diagnostically and therapeutically in a mammalian body are also provided.
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