PROCESS OF ENANTIOMERIC ENRICHING A MIXTURE OF TWO ENANTIOMERIC CHIRAL AMINES

摘要

amines in which the amino is placed at the secondary carbon atom, which is chiru00e1lnu011b substituovu00e1n residues r.sup.1.n.a r.sup.2.n. where r.sup.1.n.a r.sup.2.n.represent alkyl or arylskupiny or substituted enzyme neinhibuju00edcu00ed group, while r.sup.1. n.se differs from r.sup.2.n.structure or chiralitou is possible enantiomericky enrich, i.e.enrich one of the enantiomers of omega amino acid transaminases, which has the characteristic that preferentially transmits one of the two chiru00e1lnu00edch amines to the ketone.the transformation is carried out in the presence of aminoakceptoru.whereas the reaction's equilibrium, it can carry out backwards.and in this case may serve to stereoselektivnu00ed synthesis one chiral forms of amine by cited transaminases to the ketone in the presence of aminodonoru.u0155