USE OF VITAMIN D DERIVATIVE FOR TREATING DERMATOLOGICAL STATES, VITAMIN D DERIVATIVE, PROCESS OF ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF

摘要

Relates to compounds of formula (i), wherein: X is CH2 = exists or not; and () - ch (CH3) - (n) - C (o) - OR1, (b) - ch (CH3) - CH2O - C (o) - (R2, or (c) - C (o) - Where: OR1; and (b)Then X and the link of Strokes in the pentagonal ring is not exist; Z H; is ch2r3 - or - CH2 - ch2r3; r1 is lower alkyl, cycloalkyl or cycloalkyl, Methyl alkyl; R2 is lowerCycloalkyl or R3, R3 is lower or hidroxialquilo hidroxicicloalquilo, among others; n is 1.Also refers to the procedure for the preparation of compounds of formula I, which comprises: Separating Protective groups hydroxy substituents In The Z and y.These compounds are used as queratinizantes in the treatment of diseases such as psoriasis, acne and Skin fotodanada