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Use of Benzodiazepine Compounds for the Preparation of a Pharmaceutical Preparation Against Excitations of Excitatory Amino Acids in the Central Nervous System
Use of Benzodiazepine Compounds for the Preparation of a Pharmaceutical Preparation Against Excitations of Excitatory Amino Acids in the Central Nervous System
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机译:苯二氮卓类化合物在制备抗中枢神经系统兴奋性氨基酸兴奋剂的药物制剂中的用途
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摘要
The invention relates to the use of a benzodiazepine compound having the formula CHEM wherein R3 is hydrogen, C1-8-alkyl which may be branched, or cycloalkylmethyl; R7 and R8 are independently hydrogen, halogen, CF3, CN, NO2, NH2, C1-4-alkyl or C1-4-alkoxy; and R4 is hydrogen and R5 is hydrogen or C1-7-alkyl; or R4 and R5 together signify (CH2)n wherein n is an integer of 2-3, as the active ingredient for preparing a pharmaceutical composition for treating a central nervous system disorder related to the excitatory amino acids.
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机译:本发明涉及具有式的苯二氮卓化合物的用途,其中R 3为氢,可为支链的C 1-8-烷基或环烷基甲基; R 7和R 8独立地是氢,卤素,CF 3,CN,NO 2,NH 2,C 1-4-烷基或C 1-4-烷氧基; R 4为氢,R 5为氢或C 1-7-烷基。 R 4或R 4和R 5一起表示(CH 2)n,其中n是2-3的整数,作为用于制备治疗与兴奋性氨基酸有关的中枢神经系统疾病的药物组合物的活性成分。
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