POLYPEPTIDE, DNA SEQUENCE, VACCINE COMPOSITION (OPTIONS), ANTIBODY OR ITS FRAGMENT, VACCINE, APPLICATIONS OF POLYPEPTIDE-INDICATED, DNA SEQUENCE AND ANTIBODY OR ITS FRAGMENT

摘要

New heat shock proteins (HSP) of Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus agalactiae, with an approximate molecular weight of 70-72 kDa, immunologically related polypeptides, nucleotide and corresponding amino acid sequences of HSP72 S.pneumoniae (SEQ ID NO: 4, SE, ID, SEQ ID NO: 4, SEQ ID NO: 4, SEQ ID NO: 4, SE, ID, SE, ID, 4, SEP, NO, 4, SEP, NO. 5) the nucleotide and corresponding amino acid sequences of S. pyogenes HSP70 (SEQ ID NO: 19, SEQ ID NO: 20), the nucleotide and corresponding amino acid sequences of S. agalactiae HSP70 (SEQ ID NO: 21, SEQ ID NO: 22); antibodies that bind HSP, methods using recombinant DNA to produce HSP and immunologically related polypeptides. The polypeptides, DNA sequences and antibodies obtained according to this invention can be used to obtain new diagnostic tools, prevention and / or treatment of diseases caused by streptococci. The international application was published along with an international search report.