the use of these compounds for the manufacture of asinüülhappekloriidühendite and method for the manufacture of arüüloksü - heteroarüülkarboksamiidide (straight)

摘要

The invention relates to an effective and efficient process for the preparation of azinyl acid chloride compounds of formula I, CHEM wherein Az represents an optionally substituted azinyl group, which comprises heating a trichloromethylazine of formula II Az-CCl3 wherein Az has the meaning given, with an acid, that forms an acid chloride, which can be distilled off during the reaction under reduced pressure, in the presence of an acidic catalyst; and to the use of the compounds of formula I obtained according to this process for the preparation of (hetero)aryloxyazinylcarboxamides of formula VI CHEM in which Az has the meaning given in any of the preceding claims, and Ar represents an optionally substituted aryl or heteroaryl group, R3 represents a hydrogen atom or an alkyl group, and R4 represents an optionally substituted alkyl, aryl, heteroaryl or cycloalkyl group.