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Fremgangsmåte for fremstilling av aktive stoffer fra ubrukte eller avhendede innretninger for transdermal administering av aktive stoffer og/eller fra deres produksjonsavfall
Fremgangsmåte for fremstilling av aktive stoffer fra ubrukte eller avhendede innretninger for transdermal administering av aktive stoffer og/eller fra deres produksjonsavfall
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机译:从用于经皮施用活性物质的未使用或处置的设备和/或从其生产废料中生产活性物质的方法
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摘要
The invention pertains to a process for producing a surface-structured, sheet-like semifinished product made from a thermoplastic, having the following process steps: a thermoplastic plastic material is extruded in a molten state onto a temperature-adjustable moving belt or roller surface (5) that forms a negative structure (matrix) to the desired structure, the thermoplastic plastic material emerging from an outlet front (17) that is set transverse to the direction of motion and fully contacting the surface (5) to conform with the structure; the surface (5) is in sections subjected from without to a negative pressure which is at its maximum directly before the outlet front (in the running direction of the surface) so that the cavities belonging to the matrix (25) are practically void of air when the outlet front reaches them, and these cavities are completely filled with thermoplastic plastic material; the molten thermoplastic plastic material is while still resting on the surface - solidified by cooling, with the side brought into contact with the surface assuming the corresponding surface structure; once solidified, the semifinished product is removed from the surface.
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