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PROCESS FOR SYNTHESIS OF 2-AMINO-3,5-DIHYDRO-7-SUBSTITUTED-4H PYRROLO3,2-DPYRIMIDIN-4-ONE DERIVATIVES
PROCESS FOR SYNTHESIS OF 2-AMINO-3,5-DIHYDRO-7-SUBSTITUTED-4H PYRROLO3,2-DPYRIMIDIN-4-ONE DERIVATIVES
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机译:合成2-氨基-3,5-二氢-7取代的4H吡咯并[3,2-D]嘧啶-4-酮衍生物的方法
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摘要
An improved process for the preparation of 2-amino-3,5-dihydro-7-substituted-4H-pyrrolo[3,2-d]pyrimidin-4-ones is described wherein 2,6-diamino-3,5-dihydro-7-substituted-4H-pyrrolo[3,2-d]pyrimidin-4-one is converted to a diazonium salt which is subsequently catalytically hydrogenated to the desired compound, as well as valuable intermediates used in the process.
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