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FMS-LIKE TYROSINE KINASE (FLT) AND USE AS AN IN VITRO INHIBITOR OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)
FMS-LIKE TYROSINE KINASE (FLT) AND USE AS AN IN VITRO INHIBITOR OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)
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机译:类似于FMS的酪氨酸激酶(FLT),并作为血管内皮生长因子(VEGF)的体外抑制剂
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摘要
PCT No. PCT/GB95/01213 Sec. 371 Date May 12, 1997 Sec. 102(e) Date May 12, 1997 PCT Filed May 26, 1995 PCT Pub. No. WO95/33050 PCT Pub. Date Dec. 7, 1995Disclosed is an altered, soluble form of the FLT polypeptide being capable of binding to VEGF and thereby exerting an inhibitory effect thereon, the polypeptide comprising five or fewer complete immunoglobulin-like domains, together with pharmaceutical compositions comprising the polypeptide, and various uses thereof.
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