SULPHONAMIDIC COMPOUNDS AS THERAPEUTIC AGENTS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM, METHOD OF OBTAINING NOVEL SULPHONAMIDIC COMPOUNDS AND DRUGS CONTAINING SUCH COMPOUNDS

摘要

Use of sulphonamide compounds of formula (I) is claimed for treatment of central nervous disorders. Z = a group of formula (a)-(e); R1 = H, NH2, lower alkylamino, dialkylamino or alkyl, or halo or CF3; R2 = H or lower alkyl; R3 = H, NH2, lower alkylamino, dialkylamino, alkyl or alkoxy, or halo or CF3; R4 = NH2 or halo, or lower alkylamino, dialkylamino, alkyl or alkoxy; R5 = H or halo, or lower alkylamino, dialkylamino or alkoxy; R6 = lower alkyl, alkylamino, dialkylamino or alkoxy, or halo or CF3; R7 = NH2, lower alkylamino, dialkylamino, alkoxy or alkylsulphanyl, SH, pyrrolidin-1-yl or azetidin-1-yl; R8 = NH2, lower alkylamino, dialkylamino, alkoxy or alkylsulphanyl, benzylamino, halo, pyrrolidin-1-yl or azetidin-1-yl; R9, R10 = lower alkoxy or alkylamino; R11 = H or halo; R12 = H or lower alkyl; and provided that R7 and R8 are not both OCH3.