ASYMMETRIC SYNTHESIS OF (-) 6-CHLORO-4-CYCLOPROPYL-ETHYNYL-4- -TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE

摘要

Method for synthesis of highly effective inhibitor of reverse transcriptase HIV (A) using acetylide and trifluoromethylketone, by which arises chiral product in the presence of chiral aminoalcohol.