Methods, agents and kits for detection of organophosphorus compounds.

摘要

The invention relates to novel antibodies which are specific for GENERIC GROUPS OF organophosphates, PARTICULARLY A CLASS OF PESTICIDE USE COMMON organophosphate. Also supplied compounds and methods for obtaining these antibodies, test equipment containing the antibodies and methods for their use. PARTICULARLY, they ARE PROVIDED TO ANTIBODIES objectified methacrifos organophosphorus pesticide LOW MOLECULAR WEIGHT (EG. Below 1000), PRIMFOS methyl, fenitrothion, methyl chlorpyrifos, dichlorvos and malathion. FAVORITES conjugates of the invention have the formula (II): (RO) SUB {2} P (S) -Z- [Y] -protein wherein R is as defined in SPECIFICATION z is O, SO -NH -, Y is a group separator and "protein" refers to a protein suitable for use in conjugates hapten-PROTEIN FOR THE PURPOSE OF RAISING ANTIBODIES. Typical proteins and preferred ARE BOBINO serum albumin, albumin chicken egg, limpet hemocyanin and mixtures thereof.