Endothelin antagonists: n-{{2'-{ {(4,5-dimethyl-3-isoxazolyl) amino}sulfonyl}-4-(2-oxazolyl) {1,1'-biphenyl}-2-yl}methyl} -n,3,3-trimethylbutanamide and n-(4,5-dimethyl-3-isoxazolyl) -2'-{(3,3-dimethyl-2-oxo-1-pyrrolidinyl) methyl}

摘要

The compounds N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphenyl]-2-sulfonamide, and salts thereof, useful as endothelin antagonists.