Methods of inducing immunity to lyme disease and a colorimetric assay for borreliacidal activity of antisera

摘要

A simple, colorimetric borreliacidal assay for the determination of borreliacidal activity of immune serum to Borrelia burgdorferi is disclosed. Also disclosed is a vaccine for Borrelia burgdorferi as well as methods of inducing immunity to bacteria causing Lyme disease, including B. burgdorferi and B. garinii by administering the vaccines of the present invention. Also disclosed are kits comprising one or more vials comprising the elements of the Borrelia burgdorferi vaccine. Also disclosed are vaccine formulations for Lyme disease.