首页>
外国专利>
Pyrazolo{3,4-g}quinoxaline compounds which inhibit pdgf receptor protein ty rosine kinase
Pyrazolo{3,4-g}quinoxaline compounds which inhibit pdgf receptor protein ty rosine kinase
展开▼
机译:抑制pdgf受体蛋白酪氨酸激酶的吡唑并{3,4-g}喹喔啉化合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention relates to pyrazolo[3,4-g]quinoxaline compounds exhibiting protein tyrosine kinase inhibition activity of the formula: IMAGE where: ------ may be a double bond; R, R2, R3 and R4 are as described in claim 1; a pharmaceutically acceptable salt thereof. More specifically, compounds of this invention are novel as selective inhibitors of the PDGF-R protein tyrosine kinase and can be applied as potential therapeutic agents for various disease states which are characterized by uncontrolled cellular proliferation. Further, the present invention provides pharmaceutical compositions and a method for treating such disorders comprising the administration to a patient of a PDGF receptor inhibiting effective amount of a pyrazolo[3,4-g]quinoxaline compound exhibiting protein tyrosine kinase inhibition activity. Processes for the preparation of pyrazolo[3,4-g]quinoxaline compounds are also described.
展开▼