Thermoplastic elastomeric hydrophilic polyetherurethane expandable catheter

摘要

A melt extruded cathether of thermoplastic elastomeric hydrophilic polyurethane synthesized from a diisocyanate, a polyglycol component comprising a polyethyleneoxide glycol of high molecular weight and a chain extender expands to a larger lumen size when contacted with an aqueous liquid. The catheter may include an antithrombogenic agent, antiinfective agent and radiopaque agent. The hydrophilic polyurethane may be synthesized by one-shot bulk polymerization, and may be melt extruded into the catheter tubing, and may encapsulate a stripe of a stiffening polyurethane.