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CALCITONIN SALMON ANALOGUES, THEIR PREPARATION, MEDICINAL USE AND USE AS ANALYTICAL AGENTS

机译:降钙素类似物,其制备,药物用途和作为分析剂的用途

摘要

The subject-matter of the invention are pharmaceutical non inorganic saline solutions for endonasal administration containing a) a calcitonin, preferably salmon, as acetate salt, characterized in that it further contains the organic excipients b) N-(methyl)-glucamine, c) tromethamine, d) citric acid and e) polyvinylpyrrolidone ranging from K15 to K120. These are odourless and tasteless and thus have improved patient's compliance not having the undesirable secondary effects of known compositions as well as permit a complete and accurate analysis of the active principle and develop less degradation products during storage.
机译:本发明的主题是用于鼻内给药的非无机药物盐溶液,其包含a)降钙素,优选鲑鱼,作为乙酸盐,其特征在于它进一步包含有机赋形剂b)N-(甲基)-葡糖胺,c)氨丁三醇,d)柠檬酸和e)聚乙烯吡咯烷酮,范围从K15至K120。这些无味无味,因此改善了患者的顺应性,没有已知组合物的不良副作用,并且可以对活性成分进行完整而准确的分析,并在储存期间产生较少的降解产物。

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