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Implantable polymeric device containing pharmaceutical agents and process for its production

机译:包含药剂的可植入聚合物装置及其生产方法

摘要

The device can be obtained by treating the corresponding prefabricated implantable device of polymeric material without addition of one or more agents with an organic solvent or combinations of solvents, which interacts with the implantable device in such a way that at least one of the pharmaceutically active substances which has a molecular mass which is lower than that of the polymeric material of the implants is able to penetrate into the polymeric material of the implant, after removal of the organic solvent of the pharmaceutically active substance or substances initially remain in the polymeric material of the implantable device and after implantation of the implantable device the contained pharmaceutically active substance or substances can be released again by diffusion. IMAGE
机译:通过在不添加一种或多种试剂与有机溶剂或溶剂组合的情况下处理聚合物材料的相应预制可植入设备的情况下获得该设备,该有机溶剂或溶剂的组合与可植入设备相互作用,使得至少一种药物活性物质在除去药物活性物质的有机溶剂或一种或多种最初保留在聚合物的聚合物材料中的物质后,其分子量低于植入物的聚合物材料的分子能够渗透到植入物的聚合物材料中。可植入装置,并且在植入可植入装置之后,所包含的一种或多种药物活性物质可以通过扩散再次释放。 <图像>

著录项

  • 公开/公告号EP0550875B1

    专利类型

  • 公开/公告日1998-04-29

    原文格式PDF

  • 申请/专利权人 SCHIERHOLZ JOERG DR.DR.;

    申请/专利号EP19920121785

  • 发明设计人 SCHIERHOLZ JOERG DR.DR.;

    申请日1992-12-22

  • 分类号A61L27/00;A61L29/00;A61L31/00;

  • 国家 EP

  • 入库时间 2022-08-22 02:50:41

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