TOPICAL ANTIGLAUCOMA COMPOSITIONS COMPRISING CARBONIC ANHYDRASE INHIBITORS AND BETA-BLOCKERS
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机译:包含碳酸酐酶抑制剂和Beta阻滞剂的局部抗青光眼组合物
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摘要
Ophthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of a beta-blocker and a carbonic anhydrase inhibitor to reduce the production of aqueous humor, preferably formulated as a suspension having a pH between about 6.8 and about 7.8. These compositions may additionally contain a mucomimetic anionic polymer and/or a finely-divided drug carrier substrate to provide sustained release. A method of controlling elevated intraocular pressure with these compositions is also described.
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