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Composition for transdermal delivery system containing nonsteroidal anti-inflammatory drug as an active ingredient
Composition for transdermal delivery system containing nonsteroidal anti-inflammatory drug as an active ingredient
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机译:含有非甾体抗炎药作为有效成分的透皮给药系统组合物
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摘要
This invention relates to a composition for transdermal delivery system containing a non-steroidal anti-inflammatory drug such as propionic acid derivatives (ketoprofen, etc.) and more particularly, to an improved composition for transdermal delivery system wherein said non-steroidal anti-inflammatory drug is dispersed in nonpolar polymers designed to continuously maximize thermodynamic activity and further to increase the skin permeability of said active ingredient using fatty acid, fatty acid ester, fatty acid alcohol, propylene glycol, propylene glycol fatty acid ester, oleic acid, olein alcohol, ethylene glycol monoethylether or its mixture as a solubilizing agent or permeation enhancer, if deemed necessary.
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