Human a- and b- platelet-derived growth factor receptor proteins and uses therefor.

摘要

A human α-platelet-derived growth factor receptor (α-PDGFR) protein has the amino acid sequence: (a) beginning at amino acid 1 and ending with amino acid 1089 as shown in the accompanying Figure; (b) beginning at amino acid 24 and ending with amino acid 1089 as shown in the Figure; or (c) beginning at amino acid 959 and ending with amino acid 973 as shown in the Figure. An isolated human β-platelet-derived growth factor receptor (β-PDGFR) protein consists of amino acids 967-981 of the human β-PDGFR protein. Antibodies to the α-PDGFR protein may be used in an immunoassay for the detection of α-PDGFR antigen in a biological sample. Antibodies to the β-PDGFR protein may be used in an immunoassay for the detection of β-PDGFR antigen in a biological sample.