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CYTOKINE AND HEMOPOIETIC FACTOR ENDOGENOUS PRODUCTION ENHANCER AND METHODS OF USE THEREOF

机译:细胞因子和造血因子内源性生产增强剂及其使用方法

摘要

The invention relates to medicine, in particular to pharmacology and therapy. According to the invention method of stimulating endogenous production of cytokine and hemopoietic factors comprising introducing to a mammalian body in need of stimulation of cytokine or hemopoietic factor or both, an effective amount of oxidized glutathione, its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative, for a period of time to stimulate said endogenous production to obtain a therapeutic effect, wherein said oxidized glutathione, or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative is introduced parenterally or topically. According to the invention, oxidized glutathione or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative is introduced along with an extender of the half life of said oxidized glutathione or/and its pharmaceutically acceptable salt form, or/and its pharmaceutically acceptable derivative.
机译:本发明涉及医学,尤其涉及药理学和治疗学。根据本发明,刺激细胞因子和造血因子的内源性产生的方法包括向需要刺激细胞因子或造血因子或两者的哺乳动物体内引入有效量的氧化型谷胱甘肽,其药学上可接受的盐形式或/和其药学上的活性在一段时间内刺激所述内源性产生以获得治疗效果,其中将所述氧化型谷胱甘肽或/和/或其药学上可接受的盐形式或/和其药学上可接受的衍生物肠胃外或局部引入。根据本发明,引入氧化的谷胱甘肽或/和其药学上可接受的盐形式,或/和其药学上可接受的衍生物,以及所述氧化的谷胱甘肽或/和/或其药学上可接受的盐形式,或/和其半衰期的延长剂。药学上可接受的衍生物。

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