Human protein variant kinase gene (HPK 38), its base sequence, enzyme protein and amino acid sequence thereof

摘要

The present invention relates to a novel dominant negative protein kinase gene cloned from keratinocyte, a keratinocyte of human normal skin, its nucleotide sequence, and its enzymatic protein and its amino acid sequence. As the protein mutant kinase is an important enzyme that regulates cell division, differentiation, development, etc. in the signaling system in vivo, these protein kinase can be used for the prevention and treatment of diseases caused by abnormal signal transduction.