Aquipex pyrophyllus superoxide dismutase gene sequence and protein expressed therefrom

摘要

Provided are a superoxide dismutase gene sequence of Aquifex pyrophilus, which is a very high temperature microorganism, and a protein expressed from the sequence.;Since superoxide dismutase is involved in important defense mechanisms that prevent cellular damage by oxygen, it can be used as a medicament in the treatment of inflammation, autoimmune diseases and chromosomal damage. In particular, a. Pyrophyllus is a kind of super heat-resistant bacterium that grows at an optimum temperature of 85 ° C., so the thermal stability of its superoxide dismutase is much higher than that of other microorganisms, and thus can be widely applied in pharmaceutical fields.