A method for the resolution of racemates of intermediates which in the production of 1,5 - benzothiazepines can be used

摘要

The process comprises punching out zones from a first paper sheet having one surface which is coated with thermosealable material, and cutting the sheet into a series of stripes each having indentations defined by the zones with teeth defined between the indentations. It then involves folding the teeth of each first strip about a cotton thread which advances together with the first strip to form connected tags each having a portion of the coated surface exposed. The process then comprises cutting each first strip to separate the tags, the separate tags being connected to each other by the thread of each first strip. It then comprises driving the thread amn)and-)and tags of each first strip to space the tags on the thread by lengths sufficient to engage the thread along opposite sides of bags to which the tags are to be connected.