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EXTRA CELLULAR FORM OF HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR

机译:人成纤维细胞生长因子受体的细胞外形态

摘要

A polypeptide is disclosed which is capable of binding specifically human fibroblast growth factor (bFGF) and human acidic fibroblast growth factor (aFGF) and which has: (a) the sequence shown or a part of the said sequence or (b) a said sequence (a) modified by one or more amino acid substitutions, insertions and/or deletions and/or by an extension at either or each end. A process for preparing the polypeptide, pharmaceutical compositions containing it and a DNA sequence which encodes it are also disclosed.
机译:公开了一种多肽,其能够特异性结合人成纤维细胞生长因子(bFGF)和人酸性成纤维细胞生长因子(aFGF),并且具有:(a)所示序列或所述序列的一部分,或(b)所述序列(a)通过一个或多个氨基酸取代,插入和/或缺失和/或通过在任一端或每一端的延伸进行修饰。还公开了制备该多肽的方法,包含该多肽的药物组合物以及编码该多肽的DNA序列。

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