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USE OF AMINOTHIOLESTER DERIVATIVES IN THE PHARMACEUTICAL FIELD

机译:氨基酚类衍生物在医药领域的应用

摘要

The invention concerns the use of at least an aminothiolester derivative for preparing a pharmaceutical composition for lifting the inhibition of a characteristic resistant to apoptosis induction in transformed cells, said characteristic arising from the presence of bcl2 gene in said cells. The pharmaceutical composition is more particularly for treating pathologies including breast cancer, B cell lymphoma, leukaemia, neuroblastoma, prostate adenocarcinoma, prolactinoma and other pituitary adenomas.
机译:本发明涉及至少一种氨基硫醇酯衍生物在制备药物组合物中的用途,所述药物组合物用于在转化的细胞中增强对凋亡诱导的抗性的抑制作用,所述特征源自所述细胞中bcl2基因的存在。该药物组合物更特别地用于治疗包括乳腺癌,B细胞淋巴瘤,白血病,神经母细胞瘤,前列腺腺癌,泌乳素瘤和其他垂体腺瘤的病理。

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