Process for cross-coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates

摘要

A process for preparing polycyclic aromatic compounds by cross- coupling aromatic boron compounds with aromatic halogen compounds or perfluoroalkylsulfonates in the presence of metallic palladium as catalyst comprises adding to the reactionPPa) at least one water-soluble complexing ligand andPPb) sufficient water for the reaction mixture to form an aqueous phase.PP The reaction of the invention proceeds chemoselectively so that even electrophilic groups such as esters or nitriles do not have an adverse effect on the course of the reaction.PPThe use according to the invention of a water-soluble complexing ligand in an aqueous phase enables polycyclic aromatic compounds to be prepared in very good yields and at the same time very high purity, in particular without contamination by the complexing ligands.