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Monoclonal antibody that distinguishes between phosphorylated and nonphosphorylated histone H1 and uses therefor
Monoclonal antibody that distinguishes between phosphorylated and nonphosphorylated histone H1 and uses therefor
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机译:区分磷酸化和非磷酸化组蛋白H1的单克隆抗体及其用途
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摘要
The present invention relates to: 1) A monoclonal antibody (mAb) that binds selectively to phosphorylated histone H1 and not to nonphosphorylated histone H1 and its use. In one embodiment, the mAb of the present invention binds selectively to histone H1 phosphorylated at the 12D11 epitope as defined herein, and 2) A cell producing a monoclonal antibody which binds selectively to phosphorylated histone H1 and has been shown to distinguish between histone H1 phosphorylated at the 12D11 epitope and histone H1 nonphosphorylated at this epitope.
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