Conversion of N-(4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide acetate to N-4-fluorophenyl)-2-hydroxy-N-(1-methylethyl) acetamide

摘要

The present invention provides a process for converting N-(4- fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide acetate to N-(4- fluorophenyl)-2-hydroxy-N-(1-methylethyl)acetamide. The process includes the step of hydrolyzing N-(4-fluorophenyl)-2-hydroxy-N-(1- methylethyl) acetamide acetate with water or an aqueous alkali in the presence of an aprotic, aromatic solvent.