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Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof

机译:合成的多个串联重复粘蛋白和粘蛋白样肽及其用途

摘要

The present invention relates to novel synthetic muc-1 peptides and muc-1-like analogs including at least two 20-amino acid tandem repeats of muc-1, which synthetic muc-1 and muc-1-like peptides are capable of attaining native conformation in the absence of glycosylation. The invention also relates to methods of producing the peptides. The invention further relates to uses of the peptides, such as for vaccines and diagnostic testing.
机译:本发明涉及新颖的合成muc-1肽和muc-1样类似物,其包括至少两个muc-1的20个氨基酸串联重复,合成muc-1和muc-1样肽能够获得天然的。没有糖基化的构象。本发明还涉及产生肽的方法。本发明进一步涉及所述肽的用途,例如用于疫苗和诊断测试。

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