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Treatment of urinary incontinence treatment of desethyloxybutynin use - (S) and oxybutynin - (S)
Treatment of urinary incontinence treatment of desethyloxybutynin use - (S) and oxybutynin - (S)
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机译:尿失禁治疗的去乙氧丁宁使用-(S)和奥昔布宁-(S)
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摘要
A method for treating urinary incontinence while avoiding concomitant liability of adverse effects associated with racemic oxybutynin is disclosed. The method comprises administering a therapeutically effective amount of (S)-oxybutynin, (S)-desethyloxybutynin or a pharmaceutically acceptable salt thereof, substantially free of the corresponding R enantiomer. Pharmaceutical compositions in the form of tablets and transdermal devices comprising (S)-oxybutynin or (S)-desethyloxybutynin and an acceptable carrier are also disclosed, as is a synthesis of desethyloxybutynin.
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