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Array of the CD4 gene origin which controls the unique revelation in the maturity T lymphocyte
Array of the CD4 gene origin which controls the unique revelation in the maturity T lymphocyte
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机译:CD4基因起源阵列,可控制成熟T淋巴细胞的独特揭示
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摘要
The present invention relates to compositions and methods for the expression of nucleic acids or polypeptides into mature T lymphocytes. The invention relates more specifically to methods of selective gene expression into mature T lymphocytes, based on CD4-derived regulatory sequences, such as CD4-derived enhancer sequences. The invention is particularly suited for regulating gene expression into mature T lymphocytes in vitro, ex vivo or in vivo, upon genetic modification of hematopoietic precursors and maturation thereof.
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