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For person and anti- true germ active azole chemical compound for veterinarian
For person and anti- true germ active azole chemical compound for veterinarian
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机译:用于人和兽医的真细菌活性唑化合物
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摘要
Compounds of formula (II), wherein R1 is chlorine, fluorine or trifluoromethyl; R2 is hydrogen, chlorine, fluorine or trifluoromethyl; Z is CH or N; R3, R4 and R5, the same or different are hydrogen or C1-C4 alkyl, provided that R4 is different from R5 when R3 is hydrogen; X is O or S; R6 is a C1-C5 polyfluoroalkyl group containing at least two fluorine atoms and optionally other halogen atoms selected among chlorine and bromine; and their salts with pharmaceutically acceptable acids, are described. The compounds of formula (II) are endowed with antimycotic activity for human and veterinary use.
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机译:式(II)的化合物,其中R 1为氯,氟或三氟甲基; R 2是氢,氯,氟或三氟甲基; Z为CH或N; R3,R4和R5相同或不同是氢或C1-C4烷基,条件是当R3是氢时R4与R5不同。 X是O或S; R6是含有至少两个氟原子和任选地选自氯和溴中的其他卤素原子的C1-C5多氟烷基;描述了它们及其与可药用酸的盐。具有化学式(II)的化合物具有用于人和兽用的抗霉菌活性。
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